Equipped gems level up as
Path of exile currency you make XP, getting ten percent of their base XP granted from monster kills. Your character encounters an XP penalty when revisiting lower level regions, but that punishment does not apply to gems. Thus you can certainly level gems by replaying areas which are a few levels lower than your current degree.
Each part of loot you get takes up varying levels of space in your bag. To carry as many potential things at the same time, you need to move items around and squeeze things into the allotted spaces. Even after that, your luggage is likely to fill up fast in the event that you pick up each and every thing you encounter.
The trick, then, would be to ignore items that your character can not use or are of reduced price. Item rarity is indicated by colours: White: Regular, Blue: Magic, Yellow: Rare,Orange: Unique.
You can pretty much discount white items unless you are going to head back to town and have the space to spare for them. Rarer items are often worth picking up and selling, even in the event that you have to hold onto them for a short time. And of course, any item that appears better than your existing equipment is worth grabbing -- even if you have to
buy poe orbs lose something else temporarily while you equip it.